Abstract：Objective To investigate the antimicrobial resistance of enterococcus faecalis and enterococcus faecium in our hospital for the rational use of antibiotic. Methods GPI plate was applied for bacterial identification and susceptibility testing.Whonet5 software was used for data analysis. Results Less than 50% of enterococcus faecalis and enterococcus faecium isolates were resistant to chloramphenicol and nitrofurantoin. Less than 1% of enterococcus faecalis and enterococcus faecium isolates were resistant to vancomycin. The resistance rate of enterococcus faecalis to penicillin G, high concentration gentamicin, ciprofloxacin, rifampicin and erythromycin descend year by year, and that of enterococcus faecium to ciprofloxacin, rifampicin and nitrofurantoin was opposite. In addition, the resistance rate of enterococcus faecium to most antibiotic was higher than enterococcus faecalis. Conclusions The enterococcus faecalis and enterococcus faecium is becoming multi-resistant bacteria. Antimicrobial therapy should be decided according to the results of susceptibility testing.
