Abstract：In order to analysis the clinical characteristic of necrotizing pneunomia in children, a retrospective investigation of the clinical manifestations, radiological findings, pathology, microbiology, clinical courses and outcomes of 9 children (6 males, 3 females) with necrotizing pneumonia was performed. The age range was 1-7 years (average 3.5 years). The duration of fever was 11-43 d (average 22 d). Four cases received mechanical ventilation. There were 5 cases with microbiological identification, 2 cases with Streptococcus pneumoniae, 2 cases with Mycoplasma pneumoniae and 1 case with Pseudomonas aeruginosa. The chest CT scans showed pneumonic lobar consolidation and pleural effusion in 9 cases, and small cavities in the consolidation regions in 8 cases. All 9 patients received surgical intervention, 7 with wedge resection, 1 with segmentectomy, and 1 with lobectomy. All the specimens exhibited parenchymal necrosis and acute inflammatory infiltration. All 9 patients survived. Seven patients had full clinical resolution within 6 months, and 2 patients resolved in 10 months. Streptococcus pneumoniae and Mycoplasma pneumoniae were found to be the predominant pathogens in children with necrotizing pneumonia. The chest CT scan is crucial in the diagnosis. The prognosis is good after antibiotic and surgical therapy.
朱月钮，张明军，陈菲，朱晓东. 儿童坏死性肺炎9例临床分析[J]. 微生物与感染
, 2013, 8(1): 33-37.
ZHU Yue-Niu, ZHANG Ming-Jun, CHEN Fei, ZHU Xiao-Dong. Clinical analysis of 9 children with necrotizing pneumonia. Journal of Microbes and Infections, 2013, 8(1): 33-37.