Abstract：Hepatitis B virus (HBV) infection is a major health problem in the world, especially in China. Animal model is an important tool for studying HBV biological characteristics, pathogenesis of infection, virus-host interplay, screening of novel therapeutic targets and so on. In recent years, the development of various animal models accelerates HBV-related researches, however, all the existing models have their own disadvantages. Lacking of economical and applicable animal models that could imitate the natural course of human infection has seriously restricted the further study of HBV. This paper summarizes the current HBV animal models, which could provide the help for generation of ideal animal models.
任蓉蓉1，任晓楠1， 李顺1，刘丹慧2,周晓辉1. 乙型肝炎病毒感染动物模型的研究进展[J]. 微生物与感染, 2015, 10(6): 374-380.
REN Rong-Rong1, REN Xiao-Nan1, LI Shun1, LIU Dan-Hui2, ZHOU Xiao-Hui1. A review on the animal models of hepatitis B virus infection. JOURNAL OF MICROBES AND INFECTIONS, 2015, 10(6): 374-380.
2015, Vol. 10 
