Abstract:The plague is a zoonotic disease caused by Yersinia pestis (Y. pestis). This bacterium Y. pestis has caused three deadly pandemic plague worldwide. Considering of expanding natural foci and frequent population turnover, prevention and control of plague is still grim. In this review, we mainly summarize the research progress on the virulence factors of Y. pestis, the mechanism of invasion, the intracellular replication and the dissemination mechanism in the host.
张怡, 张昊澄. 鼠疫的发病机制研究进展[J]. 微生物与感染, 2019, 14(6): 326-332.
ZHANG Yi, ZHANG Haocheng. Advances in research on the pathogenesis of plague. JOURNAL OF MICROBES AND INFECTIONS, 2019, 14(6): 326-332.