目前，临床上常用的微生物检测方法主要有分离和培养法、ELISA以及核酸检测技术等。有效的微生物富集方法不仅为后续检测工作提供帮助，而且在某些微生物含量极低的情况下，微生物富集方法甚至将决定整个检测试验的成败。本文就微生物富集方法的原理及应用研究进展做一综述。

Microbial culture, ELISA, nucleic acid testing are the main methods for clinic microbial testing today. An effective method for microbial enrichment not only will be helpful on optimizing the sensitivity of the follow-up testing, but also will determine the availability of some testing methods when the amount of microorganisms are extremely low in the sample. The research progress on microbial enrichment methods and its applications are reviewed and discussed in this report.