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| Human papillomavirus in human carcinogenesis |
| QIAN Yong-Hong1; HUANG Xia2; JIANG Chuang1 |
| 1. Department of Gynecology and Obsterics, Suzhou Municipal Hospital Suzhou Medical Center for Maternity And Child Health, Nanjing Medical University, Suzhou 215000, China; 2. Changshu NO.2 Hospital, Changshu 215500, China |
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Abstract High-risk types of human papillomavirus (HPV) may cause various tumors. The causative link between high-risk HPV and cervical cancer has been well elucidated. Recent studies have shown that HPV DNA is detectable in head and neck squamous cell carcinoma (HNSCC), esophageal carcinoma, as well as breast cancer. The mechanisms underlying HPV infection in HNSCC may be similar but not identical to that in cervical cancer. Understanding the mechanisms underlying HPV-associated carcinogenesis will be important for the HPV-associated tumor therapy.
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Received: 11 July 2011
Published: 01 January 2011
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Corresponding Authors:
QIAN Yong-Hong
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