鼠疫疫苗研究的现状与展望

魏东,赵爱华,王国治,徐苗

微生物与感染 ›› 2020, Vol. 15 ›› Issue (3) : 135-142.

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微生物与感染 ›› 2020, Vol. 15 ›› Issue (3) : 135-142. DOI: 10.3969/j.issn.1673-6184.2020.03.001
特约专稿

鼠疫疫苗研究的现状与展望

  • 魏东,赵爱华,王国治,徐苗
作者信息 +

Current research and prospects of plague vaccine

  • WEI Dong, ZHAO Aihua, WANG Guozhi, XU Miao
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摘要

鼠疫(Plague)是由鼠疫耶尔森菌(Yersina pestisY. pestis)(简称鼠疫菌)引起的一种烈性传染病,属甲类传染病,具有高度传染性和致病性。在过去的鼠疫大流行中近2亿感染者死亡。疫苗接种是疾病预防控制的重要方法。现就鼠疫疫苗的研究进展作一综述,为新疫苗的研制提供参考。

Abstract

Plague is a category A infectious disease, which is highly infectious and pathogenic. Three great plague pandemics resulted in nearly 200 million deaths in human history. Prophylactic vaccination is an important method of disease prevention and control. In this review, we summarize the current advances in research and development of plague vaccines and provide a reference for the study of new vaccines.

关键词

鼠疫 / 鼠疫耶尔森菌 / 疫苗 / 抗原

Key words

Plague / Yersinia pestis / Vaccine / Antigens

引用本文

导出引用
魏东,赵爱华,王国治,徐苗. 鼠疫疫苗研究的现状与展望[J]. 微生物与感染. 2020, 15(3): 135-142 https://doi.org/10.3969/j.issn.1673-6184.2020.03.001
WEI Dong, ZHAO Aihua, WANG Guozhi, XU Miao. Current research and prospects of plague vaccine[J]. Journal of Microbes and Infections. 2020, 15(3): 135-142 https://doi.org/10.3969/j.issn.1673-6184.2020.03.001
中图分类号: R183.9   

基金

重大新药创制国家科技重大专项(2014ZX09304311-002)

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