Acinetobacter baumannii is a multi-drug resistant opportunistic pathogen. Its pathogenic mechanism is complex and diverse, which has posed a major threat to human health. Therefore, it is imperative to investigate its pathogenic mechanism. Bacterial motility not only plays a role in the migration of bacteria, but is also closely related to virulence, drug resistance, adhesion, chemotaxis and biofilm formation. The lack of flagella caused Acinetobacter baumannii to be thought non-motile for a long time, but further research had revealed that it could move across the wet surface by twitching and surface-associated motility. The factors affecting motility mainly include type IV pili, quorum sensing, efflux pumps, chemotaxis and blue light. This article discussed the motility, influencing factors and biological effects of motility of Acinetobacter baumannii, and provided a reference for its treatment and prevention.
ZHANG Lingling1
,
CHENG Tingting2
,
WANG Chonggang1
. Research progress on motility, influencing factors and biological effects of Acinetobacter baumannii[J]. Journal of Microbes and Infections, 2023
, 18(2)
: 123
-128
.
DOI: 10.3969/j.issn.1673-6184.2023.02.009