微生物与感染
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微生物与感染  2016, Vol. 11 Issue (2): 106-110    
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92例狂犬病的临床特点及预后分析
黄富礼1,郑海三2,曹汴川1,王舟强1,钟利1,郭政毅1,黄永茂1
1.西南医科大学附属医院,泸州 646000;2.泸州市疾病预防控制中心,泸州 646600
Clinical features and prognosis of 92 cases of rabies
HUANG Fuli1, ZHENG Haisan2, CAO Bianchuan1, WANG Zhouqiang1, ZHONG Li1, GUO Zhengyi1, HUANG Yongmao1
1. The Affiliated Hospital of Southwest Medical University, Luzhou 646000, China; 2. Luzhou Center for Disease Control and Prevention, Luzhou 646600, China
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摘要: 本文旨在分析狂犬病患者的临床特点及预后,以提高对其诊断及防治的认识。通过采用病历调阅及患者家属电话问卷调查方式,描述性分析西南医科大学附属医院2002—2015年收治的92例狂犬病住院患者的一般情况、临床资料、实验室检查结果、预防接种及预后情况。92例患者中,男女比为1.6:1,96%来自农村。主要在秋季发病,犬为主要传染源。3个月以内发病者占54%(50/92)。98%患者未注射狂犬病疫苗,61%患者不知晓需接种疫苗。发病至死亡最短时间为20 h,最长为11 d。所有患者最终均死亡。结果提示,我国西部农村地区仍是狂犬病高发地区,应加大狂犬病预防知识的普及,特别是针对15岁以下儿童及40~60岁人群;同时应注意疫苗质量的监管。

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黄富礼1
郑海三2
曹汴川1
王舟强1
钟利1
郭政毅1
黄永茂1
关键词 狂犬病临床特点预后疫苗接种    
Abstract:The present paper aims to analyze the clinical features and prognosis of rabies inpatients treated in The Affiliated Hospital of Southwest Medical University during 2002-­2015. Through the review of medical records and telephone questionnaire of the relatives of rabies patients, a descriptive analysis of general status, clinical data, laboratory test results and vaccine inoculation of 92 rabies patients was made. The male to female ratio was 1.6:1, and 96% of the patients were from rural areas. Dogs were the main source of infection. The onset of the disease was mainly within the first three months of the exposure (54%). 98% of the patients did not receive the injection of rabies vaccine before the reported exposure. All the patients died. The minimum duration from symptom onset to death was 20 h, and the maximum duration was 11 d. In conclusion, rabies is still at high risk in the rural areas of western China. The health education and publicity of knowledge of rabies prevention should be strengthened, especially for the protection of children less than 15 years and the population aged 40-­60 years.

Key wordsRabies    Clinical feature    Prognosis    Vaccination
基金资助:泸州市科技局资助项目(2014-S-45[7/12])

通讯作者: 黄永茂   
引用本文:   
黄富礼1,郑海三2,曹汴川1,王舟强1,钟利1,郭政毅1,黄永茂1. 92例狂犬病的临床特点及预后分析[J]. 微生物与感染, 2016, 11(2): 106-110.
HUANG Fuli1, ZHENG Haisan2, CAO Bianchuan1, WANG Zhouqiang1, ZHONG Li1, GUO Zhengyi1, HUANG Yongmao1. Clinical features and prognosis of 92 cases of rabies. JOURNAL OF MICROBES AND INFECTIONS, 2016, 11(2): 106-110.
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