Abstract:The present paper aims to investigate the herpes simplex virus (HSV) infection in neonates. From November 2010 to June 2011, fresh neonatal cord blood was collected from 51 neonates in a Maternity and Children Hospital and transported immediately to our laboratory. After DNA extraction from the samples, nested-polymerase chain reactions (PCR) were performed by using HSV-1 gD gene- and HSV-2 gG gene-specific primers to detect congenital HSV-1 and HSV-2 infections respectively. The PCR products were sequenced toconfirm the HSV infections.. The results indicated that the infection rate of HSV-1 and HSV-2 were 23.53% and 25.49% respectively. The HSV-1/HSV-2 co-infection rate was 7.84%. This study suggests that early diagnosis and treatment of neonatal HSV infection is critical for the prevention of diseases caused by HSV infection.
任鹏1,姚娟1,金艳2,李法锦1,汪晓婷1,葛俊1,江龙凤1,赵蕾1,吉阳1,王明丽1. 51例新生儿脐带血单纯疱疹病毒的检测[J]. 微生物与感染
, 2012, 7(2): 95-98.
REN Peng1, YAO Juan1, JIN Yan2, LI Fa-Jin1, WANG Xiao-Ting1, GE Jun1, JIANG Long-Feng1, ZHAO Lei1, JI Yang1, WANG Ming-Li1. Detection of herpes simplex virus infection in umbilical cord blood in 51 neonates. Journal of Microbes and Infections, 2012, 7(2): 95-98.