Follow-up of 49 human immunodeficiency virus antibodyindeterminate subjects in Dehong Dai and Jingpo Nationality Autonomous Prefecture of Yunnan Province
YANG Jin1, LI Dan2, WANG Ji-Bao1, LI Yan-Ling1, DUAN Xing1, XIANG Li-Fen1, YE Run-Hua1, YANG Yue-Cheng1, GONG Yu-Rong1, GAO Jie1, JIANG Yan2, DUAN Song1
1. Dehong Dai and Jingpo Nationality Autonomous Prefecture Center for Disease Control and Prevention, Mangshi 678400, China; 2. State Key Laboratory for Infectious Disease Control and Prevention, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Abstract：A total of 49 subjects with human immunodeficiency virus (HIV) antibody-indeterminate in Dehong Dai and Jingpo Nationality Autonomous Prefecture of Yunnan Province from 2008 to 2011 were analyzed. The population distribution, Western blotting (WB) bands and follow-up results of antibody were investigated to reveal the existing problems and possible improvement. All the subjects were from the HIV Confirmatory Laboratory of Dehong Dai and Jingpo Nationality Autonomous Center for Disease Control and Prevention and the results were decided by the National Guideline for Detection of HIV/AIDS (2009 Edition). 49 (2.00%) cases with indeterminate HIV antibody in 2452 samples were found, mainly in the population of voluntary counseling and testing (26.53%). The ratio of S/CO was distributed from <1 to ≥10, but the seroconversion rate of cases with S/CO≥10 was as high as 83.33% (5/6). The main bands were p24 and gp160. 27 patients were successfully followed up, of which 8 turned positive. The positive conversion rate was 29.63%（8/27）. As indeterminate HIV antibody results may exist in window period of HIV infection in patients with other diseases and even healthy people in certain physiological periods, all the laboratory procedures need good quality control. Other detection methods and epidemiological survey of acquired immunodeficiency syndrome (AIDS) should be combined to make accurate diagnosis.
杨锦1 ，李丹2，王继宝1，李艳玲1，段星1，项丽芬1，叶润华1，杨跃诚1，龚渝蓉1，高洁1，蒋岩2，段松1. 云南省德宏傣族景颇族自治州49例人类免疫缺陷病毒抗体不确定者的追踪研究[J]. 微生物与感染
, 2013, 8(1): 21-25.
YANG Jin1, LI Dan2, WANG Ji-Bao1, LI Yan-Ling1, DUAN Xing1, XIANG Li-Fen1, YE Run-Hua1, YANG Yue-Cheng1, GONG Yu-Rong1, GAO Jie1, JIANG Yan2, DUAN Song1. Follow-up of 49 human immunodeficiency virus antibodyindeterminate subjects in Dehong Dai and Jingpo Nationality Autonomous Prefecture of Yunnan Province. Journal of Microbes and Infections, 2013, 8(1): 21-25.
