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| Analysis on antibiotic resistance of 126 strains of Neisseria gonorrhoeae and an examination of integrated traditional and Western therapies on infection |
| PAN Wei-hua;LIAO Wan-qing |
| Department of Dermatology,Changzheng Hospital, Second Military Medical University,Shanghai 200003,China |
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Abstract Objective To monitor antibiotic resistance of Neisseria gonorrhoeae and to test the validity of an integrated traditional and Western medicine therapy regimen. Methods One hundred twenty-six strains of clinically collected Neissena gonorrhoeae were analyzed. A rapid quantitative method of minimum inhibitory concentration (MIC) was used to test 15 anti-microbial agents against 82 strains of Neissena gonorrhoeae, controlled by the Kirby-Bauer, or paper diffusion, method. Patients were treated with ceftriaxone, a third generation cephalosporin antibiotic and traditional medicine. Results There was no difference between the rapid quantitative method and paper diffusion method in detecting antibiotic sensitivity.The antibiotic resistance rate to ciprolloxacin was 75.40% and all strains ( 100%) were sensitive to ceftriaxone. Following the integrated treatment regimen, all patients were cured of their infection. Conclusion The sensitivity of Neisseria gonorrhoeae to ceftriaxone has been steady over the past 6 years, but the antibiotic resistance rate to ciprofloxacin has incresaed. Integrated traditional and Western medicines afforded patients complete recovery from gonorrhea infection.
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Received: 01 January 1900
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Corresponding Authors:
LIAO Wan-qing
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