微生物与感染
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JOURNAL OF MICROBES AND INFECTIONS
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Mycobacterium smegmatis: a model bacterium for tuberculosis and its current roles in research of infection and immunity
HOU Xiao-Qing, LIU Dan, WANG Yi
Department of Immunology and Pathogen Biology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China

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Abstract  Mycobacterium smegmatis (M. smegmatis) is a Gram­positive saprophytic bacterium, with the characteristics of fast­growing, non­pathogenicity as well as the highly homologous genes and similar cellular structure with Mycobacterium tuberculosis (M. tuberculosis). M. smegmatis is an ideal model for mycobacterial infection and other related immune and infectious diseases. The applications of M. smegmatis in anti­tuberculosis infection, immunoregulation and control of non­tuberculosis infection are reviewed in the present paper.

Key wordsMycobacterium smegmatis      Infection      Immunity     
Received: 26 February 2014      Published: 25 December 2014
Corresponding Authors: WANG Yi   
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HOU Xiao-Qing
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HOU Xiao-Qing,LIU Dan,WANG Yi. Mycobacterium smegmatis: a model bacterium for tuberculosis and its current roles in research of infection and immunity[J]. JOURNAL OF MICROBES AND INFECTIONS, 2014, 9(4): 238-244.
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http://jmi.fudan.edu.cn/EN/      OR     http://jmi.fudan.edu.cn/EN/Y2014/V9/I4/238
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