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Current applications of next-generation sequencing technology in Mycobacterium tuberculosis research |
XU Peng, GAN Ming-yu, GAO Qian |
Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China |
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Abstract Tuberculosis caused by Mycobacterium tuberculosis (M. tuberculosis) is the second important infectious disease in the world, and nextgeneration sequencing technology provides an effective research method to study the genome of M. tuberculosis. The current applications of nextgeneration sequencing technology in the study of M. tuberculosis from the aspects of epidemiology, drug resistance, evolution and related bioinformatics are reviewed.
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Received: 10 March 2014
Published: 25 February 2015
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Corresponding Authors:
GAO Qian
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