The outbreak of Novel coronavirus pneumonia in Wuhan have significantly threatened to the global health, especially to China. The potential of the secondary invasive fungal infection of Novel coronavirus pneumonia is an important factor threatening the life, especially the ones in severe medical conditions. Beside comprehensive fungal examinations for patients with high risks, support for novel detective techniques and novel effective approaches to inactivate pathogenic microbes are urgently needed. These strategies will provide substantial basis for overcoming novel coronavirus pneumonia as well as the secondary fungal infection.