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Nitric Oxide, Human papillomavirus and Cervical Cancer |
WEI Lan-Lan; LIU Shuang; GU Hong-Xi; ZHANG Feng-Min |
1. Department of Microbiology, Harbin Medical University, Harbin 150086, China; 2. Department of Genetics, Jiamusi University, Jiamusi 154007, China |
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Abstract Human papillomavirus(HPV) infection is an important causes of cervical cancer. From HPV infection to carcinogenesis , a number of co-factors are required. All the co-factors can cause the increase of local concentration of nitric oxide. The nitric oxide can affect the transcription and translation of HPV, but also play an important regulatory role in carcinogenesis. Clarifying the relationship of nitric oxide, human papillomavirus infection and cervical cancer is very important to develop experimental drug platform.
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Received: 13 July 2010
Published: 25 March 2011
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Corresponding Authors:
WEI Lan-Lan
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