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In vitro and in vivo models for neurological complications in hand, foot and mouth disease caused by enterovirus 71 infection |
Liu Yan, Chen Li-Qin |
Department of Forensic Medicine, Inner Mongolia Medical University, Hohhot 010059, China |
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Abstract Enterovirus 71 (EV71) infection leads to hand, foot and mouth disease (HFMD) and neurological complications. It has caused many pandemics worldwide. In order to develop effective medicines and vaccines to treat HFMD caused by EV71, the researchers have been studying EV71 pathogenesis using susceptible cells and experimental animals. The in νitro and in vivo models are summarized in this paper.
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Received: 06 January 2013
Published: 25 June 2013
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Corresponding Authors:
Chen Li-Qin
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