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Clinical analysis of Chlamydia trachinomatis urogenital tract infection in patients with sexually transmitted diseases via real-time fluorescent polymerase chain reaction |
YOU Yong-Yan, GONG Kuang-Long, GONG Xiang-Dong,SHA Zhong, ZHANG Jin-Ping, SUN Hou-Hua |
Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China |
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Abstract The clinical and laboratory analysis of 380 urogenital tract secretion samples from sexually transmitted diseases patients for Chlamydia trachomatis detection was performed by polymorphonuclear leukocyte count and fluorescent real-time polymerase chain reaction (PCR). The results showed that of 216 male patients 92.6% presented urethral polymorphonuclear leukocyte count ≥5, and 62 cases (28.70%) were Chlamydia trachomatis-positive detected by PCR. There were 30 case with Chlamydia trachomatis and Neisseria gonorrheae coinfection (13.98%). Of 164 female patients, 53.0% presented cervical canal polymorphonuclear leukocyte count ≥10, and 33 cases (20.1%) were Chlamydia trachomatis-positive detected by PCR. The results indicate that the application of real-time fluorescent PCR can improve positive detection rate of Chlamydia trachomatis and control its spread in sexually transmitted disease clinics.
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Received: 23 January 2013
Published: 01 January 2013
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Corresponding Authors:
GONG Kuang-Long
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Cite this article: |
GONG Kuang-Long. Clinical analysis of Chlamydia trachinomatis urogenital tract infection in patients with sexually transmitted diseases via real-time fluorescent polymerase chain reaction[J]. Journal of Microbes and Infections, 2013, 8(3): 153-156.
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URL: |
http://jmi.fudan.edu.cn/EN/ OR http://jmi.fudan.edu.cn/EN/Y2013/V8/I3/153 |
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