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Progress on interactions between enterovirus 71 and innate immunity |
ZHANG Xiaolong, LI Qihan |
Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China |
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Abstract Enterovirus 71 (EV71) is a pathogen for hand, foot and mouth disease (HFMD), and its prevalence is a great challenge to public health. Pathogenesis of EV71 is closely related to a panel of host innate immune responses, such as escape of interferon response, suppression of nuclear factor κB (NF-κB) signaling pathway and interactions between virus and innate immune cells. This review focuses on the new progress on interactions between EV71 and host innate immunity.
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Received: 29 December 2015
Published: 25 April 2016
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Corresponding Authors:
LI Qihan
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