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Laboratory diagnosis of Zika virus infection |
SONG Zhigang1, WANG Wei1, HU Yunwen1,2 |
1. Department of Pathogen Detection and Biological Safety, Shanghai Public Health Clinical Center Affiliated to Fudan University, Shanghai 201508, China; 2. Department of Medical Microbiology and Parasitology, Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China |
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Abstract Zika virus (ZIKV) is an arthropod-borne virus of the family Flaviviridae. Recently,the virus caused a large scale epidemic in Americas with a trend of global spreading, and constituted a Public Health Emergency of International Concern (PHEIC). The diagnosis of Zika virus disease is mainly based on the pathogen detection in the laboratory. In this review, the present methodologies of Zika virus detection including nucleic acid detection, serological detection, and virus isolation are summarized.
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Received: 18 March 2016
Published: 25 June 2016
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Corresponding Authors:
HU Yunwen
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