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| Etiological analysis of influenza in children from a sentinel surveillance hospital in Shanghai during 2013-2015 |
| WANG Ping, ZHAO Wenliang, CAI Mingyi, SHEN Qi, REN Jing, HE Yongpin |
| Jingan District Center for Disease Control and Prevention, Shanghai 200041, China |
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Abstract The present study aims to investigate the epidemiological characteristics of influenza in Shanghai children during 2013-2015, and to provide evidence-based data for influenza control and prevention. The throat swab samples were collected from the influenza-like cases at a sentinel surveillance hospital in Shanghai during 2013-2015, according to the National Influenza Surveillance Program and Influenza Virus and Experimental Technology. The samples were subjected to real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for influenza virus detection. A total of 3 359 samples were collected during 2013-2015, and 540 samples were influenza virus-positive, including 105 influenza A (H1N1), 158 influenza B and 277 H3 subtype, with a positive detection rate of 16.08%. The positive rates of influenza virus were 10.02%, 19.02% and 20.81% in 2013, 2014 and 2015, respectively. The detection rate was the lowest (7.67%) in the infants younger than 1.0 year and the highest (31.83%) in the children older than 7.0 years. The results showed that the peak of influenza epidemic appeared twice in one year. The peak of detection rate of influenza B and H1N1 appeared in winter and spring (December to March), whereas the peak in July to September was caused by H3. The predominant type of influenza virus changed from H3 to H3 and B after 2013. The results suggest that the predominant subtype of influenza virus in children has changed after 2013 in this sentinel surveillance hospital, and the monitoring of influenza B should be strengthened.
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Received: 31 March 2016
Published: 25 December 2016
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Corresponding Authors:
HE Yongpin
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2016, Vol. 11 
