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| Screening of pulmonary tuberculosis in entry applicants in Shanghai port during 2014-2015 |
| QIU Jin, JU Zhiying, LI Jun, WANG Jian, MENG Chengyan |
| Shanghai International Travel Healthcare Center, Shanghai 200335, China |
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Abstract In order to prevent the cross-border transmission of tuberculosis (TB)，tuberculosis screening was performed on each entry applicant older than 14 years in Shanghai port during 2014-2015. Suspected tuberculosis patients were selected by history enquiry, physical examination and chest X-ray scanning. Thereafter, sputum smear and culture, T-SPOT.TB assay and Xpert MTB/RIF test were applied in the suspected tuberculosis patients. In total, 215 persons were suspected of tuberculosis in Shanghai port during 2014-2015, with the detection rate of 229.76/100 000. Among them, 33 were confirmed as pulmonary tuberculosis, with confirmation rate of 15.3%. In all suspected patients，95 (44.2%) and 78 (36.3%) cases were subjected to T-SPOT.TB assay and Xpert MTB/RIF test respectively. The sensitivity and specificity of T-SPOT.TB assay were 100% and 49.4% compared with sputum culture results as the standard of diagnosis. The sensitivity and specificity of Xpert MTB/RIF test were 87.5% and 96.8% comparatively. Among 33 confirmed tuberculosis patients, 25 (75.8%) left Shanghai, 15 (45.5%) accepted anti-tuberculosis treatment for 2 weeks before leaving, and 8 (24.2%) cases were lost. The results suggest that the confirmation rate of tuberculosis in Shanghai port is relatively low in suspected cases. T-SPOT.TB assay with higher sensitivity and Xpert MTB/RIF test with higher specificity can be complementary and performed simultaneously in suspected cases to improve the detection rate of tuberculosis. All the confirmed and suspected tuberculosis cases should be managed and followed up in the future during the applicant’s stay in China.
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Received: 05 May 2016
Published: 25 October 2016
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Corresponding Authors:
MENG Chengyan
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2016, Vol. 11 
