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Morphological transformation of rod-shaped bacterial cells: mechanisms and biological impacts |
WANG Lei1,*, ZOU Lin1,*, LI Mengjie1, HOU Linlin1, CHEN Xiaoming2, LIU Wei2, SUN Guiqin3, CHEN Li1 |
1. Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China; 2. Key Laboratory of Research on Hydraulic and Hydro-Power Equipment Surface Engineering Technology of Zhejiang Province, Hangzhou 310024, Zhejiang Province, China; 3. College of Medical Technology, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China |
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Abstract Cell shape is a basic core feature for bacterial classification and identification. Although a bacterium could be defined as coccus, bacillus, vibrio or spirochete, morphological transformations were observed under various physiological and pathological conditions. In this paper, the molecular mechanisms of rod-shaped bacterial morphological transformation are reviewed, and the biological impacts of morphological transformation under nutritional deficiency, radiation, antibiotic treatment and attacking by host immune systems are discussed.
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Received: 03 September 2018
Published: 25 April 2019
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Corresponding Authors:
CHEN Li
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