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| Vaccine development for syphilis |
| ZHENG Kang1, LIU Anyuan1,2, WU Yimou1 |
| 1. Institution of Pathogenic Biology, Medical College, University of South China, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang, 421001, China; 2. The Second Affiliated Hospital of University of South China, Hengyang 421001, China |
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Abstract Syphilis is a sexually transmitted infection caused by Treponema pallidum subsp. Pallidum (T. pallidum), Over 90% of syphilis cases occur in low- and middle-income countries. Studies indicated that elimination of T. pallidum requires enhanced public health screening, treatment and vaccination. This article provides an overview of the need for development of a syphilis vaccine, summarizes the information and delivery system and candidate antigens in development, and analyzes the development strategies for T. pallidum vaccine.
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Received: 22 April 2019
Published: 25 June 2019
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Corresponding Authors:
WU Yimou
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2019, Vol. 14 
