微生物与感染
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JOURNAL OF MICROBES AND INFECTIONS  2019, Vol. 14 Issue (6): 326-332    DOI: doi:10.3969/j.issn.1673-6184.2019.06.002
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Advances in research on the pathogenesis of plague
ZHANG Yi, ZHANG Haocheng
Department of Infection Disease, Huashan Hospital, Fudan University, Shanghai 200040, China

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Abstract  The plague is a zoonotic disease caused by Yersinia pestis (Y. pestis). This bacterium Y. pestis has caused three deadly pandemic plague worldwide. Considering of expanding natural foci and frequent population turnover, prevention and control of plague is still grim. In this review, we mainly summarize the research progress on the virulence factors of Y. pestis, the mechanism of invasion, the intracellular replication and the dissemination mechanism in the host.
Key wordsPlague      Yersinia pestis      Pathogenesis      Virulence factors     
Received: 26 November 2019      Published: 25 December 2019
Corresponding Authors: zhang haocheng   
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ZHANG Yi
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Cite this article:   
ZHANG Yi,ZHANG Haocheng. Advances in research on the pathogenesis of plague[J]. JOURNAL OF MICROBES AND INFECTIONS, 2019, 14(6): 326-332.
URL:  
http://jmi.fudan.edu.cn/EN/doi:10.3969/j.issn.1673-6184.2019.06.002     OR     http://jmi.fudan.edu.cn/EN/Y2019/V14/I6/326
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