Advances in research on the pathogenesis of plague
ZHANG Yi, ZHANG Haocheng
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Department of Infection Disease, Huashan Hospital, Fudan University, Shanghai 200040, China
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Received
Published
2019-11-26
2019-12-25
Issue Date
2019-12-25
Abstract
The plague is a zoonotic disease caused by Yersinia pestis (Y. pestis). This bacterium Y. pestis has caused three deadly pandemic plague worldwide. Considering of expanding natural foci and frequent population turnover, prevention and control of plague is still grim. In this review, we mainly summarize the research progress on the virulence factors of Y. pestis, the mechanism of invasion, the intracellular replication and the dissemination mechanism in the host.
ZHANG Yi, ZHANG Haocheng.
Advances in research on the pathogenesis of plague[J]. Journal of Microbes and Infections. 2019, 14(6): 326-332 https://doi.org/doi:10.3969/j.issn.1673-6184.2019.06.002