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The phageresistance mechanisms of bacteria and the corresponding responses in bacteriophages |
LI Qingtian1, GUO Xiaokui2 |
1. Department of Laboratory Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; 2. Institute for Global Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China |
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Abstract Bacteriophage is one of the most abundant and longstanding individuals in the biosphere of the earth. Bacteriophage is also one of the most characteristic candidates to deal with antibiotic resistant bacterial infections. In this paper, we discussed the phageresistance mechanism of bacteria and bacteriophages’ responses from the aspects of bacteria and phages interactions, such as inhibition of the bacteriophage adsorption, super infection exclusion, restriction modification system, CRISPRCas, and abortive infection.
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Received: 31 December 2019
Published: 25 October 2020
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Corresponding Authors:
GUO Xiaokui
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