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JOURNAL OF MICROBES AND INFECTIONS  2020, Vol. 15 Issue (3): 179-185    DOI: 10.3969/j.issn.1673-6184.2020.03.007
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Application of nanopore sequencing technology in detection and study of viral infectious diseases
CUI Xiaoxian, LI Yunyi, YANG Yuying, ZHANG Xi, LI Chongshan
Division of Microbiology, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China

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Abstract  Rapid identification of pathogens is the basis for clinic diagnose and infectious disease prevention and control. High throughput sequencing technology breaks through the limitation of traditional detection methods, such as timeliness and sensitivity, providing an efficient way for clinical detection and research. In this review, the development of high throughput sequencing technology was discussed, mainly by introducing the three-generation nanopore sequencing technology. At the same time, the application of nanopore sequencing technology about the detection and study in viral infectious diseases were reviewed, and the application prospects and possible problems are prospected.
Key wordsViral infectious diseases      Molecular diagnostic      High throughput sequencing      Three generation sequencing technology of nanopore     
Received: 06 November 2019      Published: 25 June 2020
ZTFEL: R373  
  R446  
Corresponding Authors: LI Chongshan   
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CUI Xiaoxian
LI Yunyi
YANG Yuying
ZHANG Xi
LI Chongshan
Cite this article:   
CUI Xiaoxian,LI Yunyi,YANG Yuying等. Application of nanopore sequencing technology in detection and study of viral infectious diseases[J]. JOURNAL OF MICROBES AND INFECTIONS, 2020, 15(3): 179-185.
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http://jmi.fudan.edu.cn/EN/10.3969/j.issn.1673-6184.2020.03.007     OR     http://jmi.fudan.edu.cn/EN/Y2020/V15/I3/179
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