Application of nanopore sequencing technology in detection and study of viral infectious diseases

CUI Xiaoxian, LI Yunyi, YANG Yuying, ZHANG Xi, LI Chongshan

Journal of Microbes and Infections ›› 2020, Vol. 15 ›› Issue (3) : 179-185.

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Journal of Microbes and Infections ›› 2020, Vol. 15 ›› Issue (3) : 179-185. DOI: 10.3969/j.issn.1673-6184.2020.03.007
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Application of nanopore sequencing technology in detection and study of viral infectious diseases

  • CUI Xiaoxian, LI Yunyi, YANG Yuying, ZHANG Xi, LI Chongshan
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Abstract

Rapid identification of pathogens is the basis for clinic diagnose and infectious disease prevention and control. High throughput sequencing technology breaks through the limitation of traditional detection methods, such as timeliness and sensitivity, providing an efficient way for clinical detection and research. In this review, the development of high throughput sequencing technology was discussed, mainly by introducing the three-generation nanopore sequencing technology. At the same time, the application of nanopore sequencing technology about the detection and study in viral infectious diseases were reviewed, and the application prospects and possible problems are prospected.

Key words

Viral infectious diseases / Molecular diagnostic / High throughput sequencing / Three generation sequencing technology of nanopore

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CUI Xiaoxian, LI Yunyi, YANG Yuying, ZHANG Xi, LI Chongshan. Application of nanopore sequencing technology in detection and study of viral infectious diseases[J]. Journal of Microbes and Infections. 2020, 15(3): 179-185 https://doi.org/10.3969/j.issn.1673-6184.2020.03.007
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