Current research progress on host innate immune escaping by Salmonella
XU Nuo1, ZHOU Bangyue1, SHI Yi1, PAN Xingyuan1,2, QIN Tao3, XU Zhengzhong4, YIN Yinyan1,2,4
1. Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, China; 2. Jiangsu Key laboratory of integrated traditional Chinese and Western Medicine for prevention and treatment of Senile Diseases, Yangzhou University, Yangzhou 225009, Jiangsu Province, China; 3. Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonosis, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, Jiangsu Province, China; 4. Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou 225009, Jiangsu Province, China
AbstractSalmonella is an important foodborne pathogen, which seriously threatens the global public health. The host innate immune response plays a significant role for resisting infection. Nowadays, Salmonella has evolved a series of strategies to escape the innate immune response for persistent infections. This review gives a detailed summarization on the new strategies of Salmonella, including receptors (TLRs, NLRs, RIPs), cytokines (IL-22 and IL-4) and mTOR signaling pathway-mediated immune escape.
XU Nuo1,ZHOU Bangyue1,SHI Yi1等. Current research progress on host innate immune escaping by Salmonella[J]. JOURNAL OF MICROBES AND INFECTIONS, 2020, 15(5): 331-336.