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| Advances in disseminated histoplasmosis |
| WANG Niuniu1，2, ZHENG Jianming1, LIU Liguang1，3 |
| 1. Infection department in Huashan hospital of Fudan University, Shanghai 200032, China; 2. Infection department in Suzhou hospital affiliated of Anhui Medical university, Suzhou 234000, Anhui Province, China; 3. Respiratory department in the 4th affiliated hospital of Anhui Medical university, Hefei 230012, Anhui Province, China |
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Abstract Histoplasmosis is a class of fungal disease mainly caused by Histoplasma capsulatum. Most of the immunocompetent people infected with Histoplasma capsulatum were self-limited and had few clinical symptoms. However, those with immunodeficiency, organ transplants and a history of travel in epidemic areas may suffer from disseminated histoplasmosis characterized by urgent onset, rapid development, and high mortality. Histoplasmosis was once considered to be an epidemic mycosis in the western hemisphere. Although it was regarded as a rare and imported infection in China, indigenous cases have been reported recently. To prevent misdiagnosis of the disease, epidemiological status, susceptible population, clinical manifestations, diagnostic methods and treatment progresses of disseminated histoplasmosis are reviewed in this paper.
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Received: 22 August 2019
Published: 25 December 2020
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Corresponding Authors:
ZHENG Jianming
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2020, Vol. 15 
