The &ldquo;intestinal mechanism&rdquo; of anti-diabetes drugs

FENG Yuwei1; ZHANG Feng2; 3; 1; WANG Xuesong3; 4; 1; XIA Yanping2; 3; HUA Jiao5; 1; CAO Hong1; 2; 3; 6

doi:10.3969/j.issn.1673-6184.2021.01.009

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Journal of Microbes and Infections ›› 2021, Vol. 16 ›› Issue (1) : 63-70. DOI: 10.3969/j.issn.1673-6184.2021.01.009

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The “intestinal mechanism” of anti-diabetes drugs

FENG Yuwei¹, ZHANG Feng^2，3，1, WANG Xuesong^3，4，1, XIA Yanping^2，3, HUA Jiao^5，1, CAO Hong^{1，2，3，6}

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Abstract

Diabetes is one of the most serious public health problems in China. Recently, growing evidence demonstrated that gut microbiota are closely involved in the onset and development of type 2 diabetes. Studies also indicated that anti-diabetic drugs can achieve the effect of lowering blood glucose by modulating gut microbiota to carry out “molecular dialogue” with the host. This paper summarized the recent publications related to the intestinal mechanism of anti-diabetic drugs.

Key words

Diabetes mellitus / Gut microbiota / Anti-diabetic drug / Glucolipid metabolism

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FENG Yuwei1, ZHANG Feng2，3，1, WANG Xuesong3，4，1, XIA Yanping2，3, HUA Jiao5，1, CAO Hong1，2，3，6. The “intestinal mechanism” of anti-diabetes drugs[J]. Journal of Microbes and Infections. 2021, 16(1): 63-70 https://doi.org/10.3969/j.issn.1673-6184.2021.01.009