Severe meningitis caused by Cryptococcus neoformans infection: a case report

XIE Yun-Qi; YUAN Yun-Sheng; LIN Xiao-Hua; HUANG Lei; RAO Li-Ying; LIU Zhen-Yi; SUO Zhi-Jun; YU Yi-Jian; CHEN Tong

doi:10.3969/j.issn.1673-6184.2024.04.005

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Journal of Microbes and Infections ›› 2024, Vol. 19 ›› Issue (4) : 227-231. DOI: 10.3969/j.issn.1673-6184.2024.04.005

Case Analysis

Severe meningitis caused by Cryptococcus neoformans infection: a case report

XIE Yunqi^1，2，YUAN Yunsheng³，LIN Xiaohua³，HUANG Lei³，RAO Liying^1，2，LIU Zhenyi^1，2，SUO Zhijun³，YU Zhijian^1，2，CHEN Zhong^1，2

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Abstract

Cryptococcus is an opportunistic pathogen that causes cryptococcal meningitis in immunocompromised patients. Cryptococcus mainly causes subacute or chronic infection, but the acute course is rare. This article introduced a case of progressive exacerbation of meningitis caused by acute infection of Cryptococcus neoformans in a diabetic patient, and to understand the factors affecting the poor prognosis of cryptococcal meningitis.

Key words

Cryptococcus neoformans meningitis / Intracranial hypertension / Diabetes / Antifungal therapy

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XIE Yunqi1, 2, YUAN Yunsheng3, LIN Xiaohua3, HUANG Lei3, RAO Liying1, 2, LIU Zhenyi1, 2, SUO Zhijun3, YU Zhijian1, 2, CHEN Zhong1, 2. Severe meningitis caused by Cryptococcus neoformans infection: a case report[J]. Journal of Microbes and Infections. 2024, 19(4): 227-231 https://doi.org/10.3969/j.issn.1673-6184.2024.04.005