Evaluation on the relationship between urethral polymorphonclear leukcyteson infections of Chlaydia trachomatis and Neisseria gonorrhoeae in male patients with utrthritis
GONG Kuang-long; YOU Yong-yan; ZHANG Jin-ping; SUN Huo-hua; SHA Zhong; GONG Xiang-dong
Evaluation on the relationship between urethral polymorphonclear leukcyteson infections of Chlaydia trachomatis and Neisseria gonorrhoeae in male patients with utrthritis
GONG Kuang-long; YOU Yong-yan; ZHANG Jin-ping; SUN Huo-hua; SHA Zhong; GONG Xiang-dong
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Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
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Received
Revised
Published
1900-01-01
1900-01-01
2008-06-25
Abstract
Objective Chlamydia trchomatis and Neisserria gonorrhoeae are the primary bacterial pathogens causing urethral infection in men.Methlend blue stain is used to detect urethral inflammation, suggestive of infection, in men and guide threapeutic dicisions. In the absence of signs, symptoms or polymorphonuclear leukocyte on methlend blue stain(PMNLs).The tctreatment is deferred on management. Studing relation about Chlamydia-infected,Gonorrhea-infeced and PMNLs who compare their clical characteristics of urethral inflammation in men. Metholds 3,000 were presenting for routine sexually transmitted disease care with uethral PMNLS count, the direct qualitive detection of Chlamydia trachomatis antigen and culture. Results: Among 3,000 eligible men,387(12.0%) had chlamydia and 415(13.8%)had gonorrhea. Among chlamydia-infected men,PMNLS per oil-immersion field were ≥5 in 242(62.5%), 1 to 4 in 59(15.2%),and none in 86(22.2%)，36(9.3%) and 141(36.4%) in men were asympomati or signs at that stage oa their infection. Among gonorrhea-infected, PMNs per oil-immersion field were ≥5 in 397(95.7%), 1 to 4 in 10(2.4%), none in 8(1.9%), 5(1.2%) and 46(11.1%) in men were asympomati or signs at that stage oa their infection. And an additional 86 were coinfeced with both organisms. PMNLs were≥5 in 76,1 to 4 in 5,none in 5. Conclusions:The paper used to analyze the ralationship of urethral inflammation PMNs,Chlamydia trachomatis and Neisseria gonorrhoeae infetion.The pations of chlamydia、gonorrhea and PMNLs in men infected have obvious difference(P<0.001). 86(22.2%) of chlamydial and 8(1.2%)of gonococcal infection had no evidence of PMNLs. It is strenuous that both of clical and testing teehnicality is important to increase dignosis for urthral inflammation in men and control sexually transmitted disease.
GONG Kuang-long; YOU Yong-yan; ZHANG Jin-ping; SUN Huo-hua; SHA Zhong; GONG Xiang-dong.
Evaluation on the relationship between urethral polymorphonclear leukcyteson infections of Chlaydia trachomatis and Neisseria gonorrhoeae in male patients with utrthritis[J]. Journal of Microbes and Infections. 2008, 3(2): 80-83
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