Epidemiological and clinical features of 30 cases of epidemic encephalitis type B

CUI Chen-Rong; WANG Feng-Bin; OU Qiang

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Journal of Microbes and Infections ›› 2009, Vol. 4 ›› Issue (3) : 162-164.

病例分析

Epidemiological and clinical features of 30 cases of epidemic
encephalitis type B

CUI Chen-Rong；WANG Feng-Bin；OU Qiang

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Abstract

The goal of the current study was aimed to examine the epidemiological and clinical features of epidemic encephalitis type B and to improve the levels of diagnosis and treatment. The clinical data of 30 patients with epidemic encephalitis type B were analyzed retrospectively. Although all people are susceptible to this disease, children were more easily affected. More than 90% of the cases occurred in summer and autumn. All patients presented with fever and intracranial hypertension. Twenty-one patients ( 70. 0% ) experienced a conscious disturbance. Fourteen patients ( 46. 7% ) presented with a tic and 8 patients ( 26. 7% ) experienced respiratory failure. Signs of meningeal irritation were positive in 20 cases and pathological signs were positive in 18 cases. The level of protein was high and leukocyte count was below300 ×10⁶ /L in cerebrospinal fluid. The contents of chloride and glucose were normal. The positive rate of epidemic encephalitis type B-specific IgM antibody in cerebrospinal fluid was 100% . Twenty-three cases were cured or improved ( 76. 7%) , 4 cases voluntarily discharged against medical advice( 13. 3% ) and 3 patients died ( 10. 0% ) . The results showed that epidemic encephalitis type B was most common in summer and autumn and that children and adolescents in epidemic areas were most susceptible. A correct diagnosis of epidemic encephalitis type B can be made by detecting specific IgM antibody in cerebrospinal fluid and blood. Symptomatic and supportive treatments are key parts of therapy.

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Epidemic encephalitis type B / Epidemiology / Diagnosis / Therapy

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CUI Chen-Rong；WANG Feng-Bin；OU Qiang. Epidemiological and clinical features of 30 cases of epidemic
encephalitis type B[J]. Journal of Microbes and Infections. 2009, 4(3): 162-164