Porcine sapovirus (PoSaV), transmitted through fecal-­oral pathway, is an enteric calicivirus causing acute gastroenteritis in pigs, and poses a serious threat to the environment­-harmony ecotype of breeding industry. Porcine sapoviruses closely related to human strains have been detected in swine. As more and more porcine and human recombinant sapoviruses have been reported, the potential risk of cross­species infections and zoonotic generation is a practical concern. However, researches on invasion, infection, mutation, migration, immunization, outbreaks, epidemiology, cross­species infection and transmission of porcine sapovirus are rare. In this review, we focus on viral morphology and resistance, genomic structure and recombinant, transmission, epidemiology and cell receptor of porcine sapovirus.