Advances in aptamers in diagnosis and treatment of infectious diseases

TIAN Yu1; ZHAO Jun2; CHEN Jingxian2; WANG Mingli2

doi:10.3969/j.issn.1673-6184.2018.06.008

Journal of Microbes and Infections >

2018 , Vol. 13 >Issue 6: 373 - 378

DOI: https://doi.org/10.3969/j.issn.1673-6184.2018.06.008

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Advances in aptamers in diagnosis and treatment of infectious diseases

TIAN Yu1 ,
ZHAO Jun2 ,
CHEN Jingxian2 ,
WANG Mingli2

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1. The First Clinical Medical College, Anhui Medical University, Hefei 230601, China; 2. Department of Microbiology, Anhui Medical University, Hefei 230032, China

Received date: 2018-05-21

Online published: 2018-12-25

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Abstract

Quick diagnosis and precise treatment of infectious diseases are two of the urgent tasks in clinical medicine. The nucleic acid aptamer is specific for target obtained by alternate screen and enrichment in vitro or systematic evolution of ligands by exponential enrichment (SELEX) technology. The application of aptamer in the diagnosis and treatment of infectious diseases is reviewed.

Key words： Aptamer; Disease diagnosis; Infectious disease

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TIAN Yu1 , ZHAO Jun2 , CHEN Jingxian2 , WANG Mingli2 . Advances in aptamers in diagnosis and treatment of infectious diseases[J]. Journal of Microbes and Infections, 2018 , 13(6) : 373 -378 . DOI: 10.3969/j.issn.1673-6184.2018.06.008

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