Corynebacterium kroppenstedtii (C. kroppenstedtii) is a member of the genus Corynebacterium. Genome sequence analysis of the C. kroppenstedtii type strain has revealed a lipophilic (lipid-requiring) lifestyle. The clinical isolates of C. kroppenstedtii have been obtained almost exclusively from female patients, and mainly from the diseased breast tissue samples of the patients with breast abscess and granulomatous mastitis (GM). However, the role of C. kroppenstedtii in breast pathologies remains unclear. This paper reviews the research progress on the correlation between C. kroppenstedtii and granulomatous mastitis.