Progress in application of phage therapy in diseases
FU Xiaomei1, WANG Yue1, CHEN Qian1, GUO Xiaokui2, LIU Chang1
1. Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; 2. School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
Abstract：With the worldwide spread of antimicrobial-resistant bacteria, phage therapy has attracted renewed attention as an effective alternative to antibiotics. On the other hand, with the development of research on the interactions between human microbiota and the host, a number of studies have focused on regulating the microbiota to affect human health. The use of phages to reduce the abundance of characteristic bacteria positively associated with disease progression has become a more precise prevention or adjuvant treatment strategy for non-infectious diseases such as cancer, alcoholic liver disease and diabetes. In this paper, the progress of phage therapy applications in infectious and non-infectious diseases was reviewed.
符小妹1，王悦1，陈倩1，郭晓奎2，刘畅1. 噬菌体疗法在疾病中的应用进展[J]. 微生物与感染, 2021, 16(6): 417-424.
FU Xiaomei1, WANG Yue1, CHEN Qian1, GUO Xiaokui2, LIU Chang1. Progress in application of phage therapy in diseases. JOURNAL OF MICROBES AND INFECTIONS, 2021, 16(6): 417-424.