The phageresistance mechanisms of bacteria and the corresponding responses in bacteriophages
LI Qingtian1, GUO Xiaokui2
1. Department of Laboratory Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; 2. Institute for Global Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
Abstract：Bacteriophage is one of the most abundant and longstanding individuals in the biosphere of the earth. Bacteriophage is also one of the most characteristic candidates to deal with antibiotic resistant bacterial infections. In this paper, we discussed the phageresistance mechanism of bacteria and bacteriophages’ responses from the aspects of bacteria and phages interactions, such as inhibition of the bacteriophage adsorption, super infection exclusion, restriction modification system, CRISPRCas, and abortive infection.
李擎天1，郭晓奎2. 细菌与噬菌体的相互抵抗作用机制[J]. 微生物与感染, 2020, 15(5): 265-270.
LI Qingtian1, GUO Xiaokui2. The phageresistance mechanisms of bacteria and the corresponding responses in bacteriophages. JOURNAL OF MICROBES AND INFECTIONS, 2020, 15(5): 265-270.
2020, Vol. 15 
