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Research progress on measuring the latent reservoir of human immunodeficiency virus |
JIN Shan, HE Yongquan , YANG Yu , ZHANG Xiaoyan |
Shanghai Public Health Clinical Center Affiliated to Fudan University, Shanghai 201508, China |
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Abstract The latent viral reservoir in resting CD4+T cells is widely recognized as a major barrier to cure human immunodeficiency virus type 1 (HIV-1) infection. A highthroughput, reliable and sensitive assay that can accurately measure the true size of the viral reservoir is urgently needed. In this review, multiple measurement methods of HIV latent reservoir are summarized.
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Received: 02 November 2015
Published: 25 February 2016
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Corresponding Authors:
ZHANG Xiaoyan
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