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| Risk factors of infections caused by linezolid-resistant Enterococcus faecalis |
| MA Xiaoyu, PU Zhangya，YAO Weiming, CHEN Zhong, WANG Hongyan, CHENG Hang, DENG Xiangbin, LI Duoyun, ZHENG Jinxin, DENG Minggui, LIU Xiaojun, DENG Qiwen, YU Zhijian |
| Department of Infectious Diseases, Shenzhen Nanshan District People’s Hospital, Shenzhen Key Laboratory for Endogenous Infection, Shenzhen 518052, China |
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Abstract To analyze the risk factors of infections caused by linezolid-resistant Enterococcus faecalis (E. faecalis), 165 cases from Shenzhen Nanshan District People’s Hospital with E. faecalis infection recorded from January 2010 to September 2015 were studied. The patients were divided into linezolid-sensitive group and linezolid-resistant/intermediate group. E. faecalis mainly came from urine culture (53.94%), and then wound secretion culture (21.82%) and bloodstream culture (6.06%). E. faecalis infection was mainly found in Department of Urology (35.76%) and Department of Hepatobiliary Surgery (9.70%). Both univariate analysis and logistic regression analysis showed that carbapenem exposure and indwelling catheter were associated with linezolid-resistant E. faecalis infections. The results suggest that the clinical application of carbapenems should be strictly controlled, and the management of nosocomial infection should be strengthened.
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Received: 25 September 2016
Published: 25 August 2017
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Corresponding Authors:
YU Zhijian
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| [1] |
LIN Fojun, PU Zhangya, CHEN Zhong, MA Xiaoyu, BAI Bing1, DENG Xiangbin, CAI Botao, XU Guangjian, HAN Xueying, XU Zhichao, ZHANG Bo, YU Zhijian, DENG Qiwen. Analysis of antimicrobial susceptibility, risk factors and clinical outcomes for bloodstream infections caused by extended-spectrum β-lactamase-producing Klebsiella pneumoniae[J]. JOURNAL OF MICROBES AND INFECTIONS, 2017, 12(5): 299-306. |
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2017, Vol. 12 
