本文报道急性神经源性肺水肿型手足口病1 例。该患儿发热伴特征性手、足、臀部皮疹和口腔疱疹,继发呼吸困难、严重高血压、肺水肿、颅内高压, 伴外周循环衰竭等症状。经过气管插管, 正压机械通气, 大剂量丙种球蛋白封闭, 大剂量肾上腺皮质激素冲击, 甘露醇、甘油果糖控制肺水肿和颅内高压, 磷酸肌酸营养心肌, 利巴韦林抗病毒等治疗, 转危为安。

A case of acute neurogenic pul monary edema caused by hand , f oot and mouth disease was reported in this paper . The chil d presented with f ever and characteristic  ashes in hands , f eet , mouth and buttocks . Respiratory difficulties , serious hypertension, pulmonary edema, and intracranial pressure were secondary to fever and rashes , complicated with peripheral circulatory failure . Intubation , positive pressure ventilation , high-dose intravenous γ-globulin , and short-term high-dose cortin were effective measures to prevent disease progression. After administration of mannitol and glycerol and fructose , pul monary edema and intracranial pressure were controlled. Furthermore , in combination with nutrition of myocardiumby creatine phosphate and antiviral therapy by ribavirin, the child was rescued.