1. 复旦大学基础医学院教育部/卫生部医学分子病毒学重点实验室，上海 200032；2. 上海市（复旦大学附属）公共卫生临床中心，上海 201508；3. 纽约血液中心Lindsley F. Kimball研究所，美国 纽约 10065
Strategies for human immunodeficiency virus cure: current status and future prospects
LI Hao-Yang1,2，QU Yu-Chen1,2，WANG Qian1,2，JIANG Shi-Bo1,2,3, LU Lu1,2
1. Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China; 2. Shanghai Public Health Clinical Center Affiliated to Fudan University, Shanghai 201508, China; 3. Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA
Abstract：The combined antiretroviral therapy (cART) has been applied to control the course of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS). However, cART requires lifelong daily treatment and strict adherence. HIV can quickly rebound after drug withdrawal because of the presence of the latent HIV reservoir in vivo. Therefore, reactivation of latent HIV and elimination of latent HIV reservoir are critical for cure of HIV infection and AIDS. Here, we review the recent advancements and future prospects on the strategies for HIV cure.
李浩洋1,2，曲玉晨1,2，王茜1,2，姜世勃1,2,3, 陆路1,2. 分析及预测治愈艾滋病的策略[J]. 微生物与感染, 2015, 10(5): 264-274.
LI Hao-Yang1,2，QU Yu-Chen1,2，WANG Qian1,2，JIANG Shi-Bo1,2,3, LU Lu1,2. Strategies for human immunodeficiency virus cure: current status and future prospects. JOURNAL OF MICROBES AND INFECTIONS, 2015, 10(5): 264-274.
