Abstract:Nucleotide-binding oligomerization domain-like receptor family pyrin domain containing (NLRP) 6 is one of the important intracellular pattern recognition receptors of host innate immunity and is involved in the regulation of infection, inflammation, tumor and metabolic diseases. By sensing pathogenic organisms such as bacteria, viruses, fungi, parasites and their products, it can regulate the anti-infection immune effect of the body and affect the outcome. This article reviews the structure and function of NLRP6 and its role in host immunity against bacterial infection.
曹宇 龚亚婷 黄瑞. NLRP6在抗细菌感染免疫中的作用研究进展[J]. 微生物与感染, 2023, 18(6): 358-363.
Yu CAO Ya-Ting GONG Rui HUANG. Advances in studies on the role of NLRP6 in host immunity against bacterial infection. JOURNAL OF MICROBES AND INFECTIONS, 2023, 18(6): 358-363.