1.General Department, Luotian First People’s Hospital, Hubei Province, Huanggang 438600, China; 2. Department of Clinical Microbiology and Immunology, Third Military Medical University, Chongqing 400038, China
Abstract:Melioidosis, caused by the inoculation, inhalation and ingestion of Burkholderia pseudomallei, is a classical tropical amphixenosis characterized by multi-abscess , tough pneumonia and fatal septicemia. The mortality rate of this disease is up to 40%. Its endemic regions are mainly among North Australia, Southeast Asia, with sporadic cases reported from North America and other areas. Melioidosis may have a wide range of clinical manifestations, varying from an acute fulminant septic illness to a chronic infection. High misdiagnosis rate, high resistance rate and long period of antibiotic therarapy combined with high relapse rate are the major barriers to treatment . With the globalization and increasing risk of imported cases, it is necessary to effectively prevent and cure melioidosis. The current research progress and clinical advice are summarized in this paper.
方静1,方瑶2. 类鼻疽的研究进展及诊疗现状[J]. 微生物与感染
, 2013, 8(2): 115-118.
FANG Jing1, FANG Yao2. Progress on research and treatment of melioidosis. Journal of Microbes and Infections, 2013, 8(2): 115-118.