Abstract:Candida species are the most prevalent opportunistic fungal pathogens in humans causing superficial and serious systemic infections. The infection process can be divided into three stages: adhesion, invasion, and host cell damage. Adhesion is the first stage of invasive Candida infection process and is precisely controlled by a lot of adhesins. Many of these adhesion-related proteins are members of glycosylphosphatidylinositol-anchored cell wall protein (GPI-CWP) family. This review is intended to summarize some important adhesion related to GPI-CWP: agglutinin-like sequence (Als), hyphal wall protein 1 (Hwp1), epithelial adhesin (Epa), and enhanced adherence to polystyrene 1 (Eap1).
严蕾,唐建国. 假丝酵母黏附相关糖基磷脂酰肌醇锚定细胞壁蛋白的研究进展[J]. 微生物与感染
, 2013, 8(3): 181-185.
YAN Lei, TANG Jian-Guo. Study of adhesion-related glycosylphosphatidylinositol-anchored cell wall proteins in Candida species. Journal of Microbes and Infections, 2013, 8(3): 181-185.