Current applications of next-generation sequencing technology in Mycobacterium tuberculosis research
XU Peng, GAN Ming-yu, GAO Qian
Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China
Abstract:Tuberculosis caused by Mycobacteriumtuberculosis (M. tuberculosis) is the second important infectious disease in the world, and nextgeneration sequencing technology provides an effective research method to study the genome of M. tuberculosis. The current applications of nextgeneration sequencing technology in the study of M. tuberculosis from the aspects of epidemiology,drug resistance, evolution and related bioinformatics are reviewed.
徐鹏,甘明宇,高谦. 二代测序技术在结核分枝杆菌研究中的应用进展[J]. 微生物与感染, 2015, 10(1): 54-60.
XU Peng, GAN Ming-yu, GAO Qian. Current applications of next-generation sequencing technology in Mycobacterium tuberculosis research. JOURNAL OF MICROBES AND INFECTIONS, 2015, 10(1): 54-60.