A case of coxsackievirus A6-caused hand, foot and mouth disease complicated with systemic herpes and cervical spinal cord involved
LI Hua-Jun1, SONG Zhi-Gang2, CAI Kang1, GONG Ying-Liang1, YU Hui-Ju1
1. Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China; 2. Shanghai Public Clinical Health Center, Shanghai 200433, China
Abstract：Hand, foot and mouth disease (HFMD) is a common acute infectious disease caused by enteroviruses, whose most common pathogens are human enterovirus 71 and coxsackievirus A16. Coxsackievirus A6 is relatively rare. Here a rare HFMD case complicated with systemic herpes and cervical spinal cord involved is reported. The rashes caused by HFMD were most commonly seen at the palm of hand and foot, hip, knee and elbow joint. The infant was developed to systemic herpes quickly and complicated with significantly increased neuron specific enolase and imaging changes of cervical spinal cord in magnetic resonance imaging (MRI). Under the treatment of anti-inflammatory, anti-virus, and supporting therapy, the systemic herpes disappeared and the infant fully recovered. Clinical physicians should paid more attention to this rare case caused by coxsackievirus A6.
李华君1，宋志刚2，蔡康1，龚莹靓1，俞慧菊1. 柯萨奇病毒A6型手足口病所致全身性疱疹并累及颈髓1例[J]. 微生物与感染, 2015, 10(5): 315-317.
LIU Hua-Jun1, SONG Zhi-Gang2, CAI Kang1, GONG Ying-Liang1, YU Hui-Ju1. A case of coxsackievirus A6-caused hand, foot and mouth disease complicated with systemic herpes and cervical spinal cord involved. JOURNAL OF MICROBES AND INFECTIONS, 2015, 10(5): 315-317.
