1. Department of Pathogen Detection and Biological Safety, Shanghai Public Health Clinical Center Affiliated to Fudan University, Shanghai 201508, China; 2. Department of Medical Microbiology and Parasitology, Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China
Abstract:Zika virus (ZIKV) is an arthropod-borne virus of the family Flaviviridae. Recently,the virus caused a large scale epidemic in Americas with a trend of global spreading, and constituted a Public Health Emergency of International Concern (PHEIC). The diagnosis of Zika virus disease is mainly based on the pathogen detection in the laboratory. In this review, the present methodologies of Zika virus detection including nucleic acid detection, serological detection, and virus isolation are summarized.
宋志刚1,王蔚1,胡芸文1,2. Zika病毒感染的实验室诊断[J]. 微生物与感染, 2016, 11(3): 137-143.
SONG Zhigang1, WANG Wei1, HU Yunwen1,2. Laboratory diagnosis of Zika virus infection. JOURNAL OF MICROBES AND INFECTIONS, 2016, 11(3): 137-143.