The pathogenetic mechanism of proteases from pathogenic fungi
SANG Junjun, LI Yingfang, PAN Weihua, LIAO Wanqing
Institute of Dermatology and Mycoses, Shanghai Key Laboratory of Medical Molecular Mycology, Key Laboratory of Fungal Diseases, Department of Dermatology, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, China
Abstract:Proteases play an important role in fungal physiology and growth and in infection of pathogenic fungi as well. Fungal proteases may be involved in adhesion, colonization, spreading and escaping from the host immune response. Some proteases are considered as allergens, which can induce asthma and allergic diseases. Knowledge of the pathogenesis of the proteases will increase our understanding about the action of each fungal protease and will help to provide clues for the diagnosis and treatment of fungal infection.
桑军军,李颖芳,潘炜华,廖万清. 病原性真菌蛋白酶致病机制研究进展[J]. 微生物与感染, 2017, 12(1): 8-13.
SANG Junjun, LI Yingfang, PAN Weihua, LIAO Wanqing. The pathogenetic mechanism of proteases from pathogenic fungi. JOURNAL OF MICROBES AND INFECTIONS, 2017, 12(1): 8-13.