Research advances in bacterial strategies for evading the
killing by mononuclear macrophages
Luo Yun-Man1; Guo Xiao-Kui2 ; Jiang Xu-Cheng1
1.Department of Pathology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; 2. Department of Medical Microbiology and Parasitology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
Abstract：Mononuclear macrophages, which protect people from many infections, play a pivotal role both in innate and acquired immune system. Meanwhile, in order to cope with the attacks of the macrophages, bacteria have evolved several effective strategies to survive and colonize the host. This paper summarizes various modes that bacteria have evolved to evade the killing by macrophages: （1）antiphagocytosis, （2）anti-degradation of the phagolysosomes, （3） inducing apoptosis or necrosis of the macrophages，and （4）inhibiting apoptosis or necrosis of the macrophages.
罗云蔓1; 郭晓奎2; 姜叙诚1 . 病原菌逃避单核-巨噬细胞杀灭策略的研究进展[J]. 微生物与感染
, 2010, 5(2): 117-120.
Luo Yun-Man1; Guo Xiao-Kui2; Jiang Xu-Cheng1. Research advances in bacterial strategies for evading the
killing by mononuclear macrophages. Journal of Microbes and Infections, 2010, 5(2): 117-120.
2010, Vol. 5 
